Histogen Welcomes Robert Kellar...

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Histogen Welcomes Robert Kellar as Vice President of Research and Development
New regenerative medicine company armed for growth in 2008

SAN DIEGO, December 20, 2007 - Histogen, Inc., a regenerative medicine company developing solutions based on the products of newborn fibroblasts, announced today that Dr. Robert Kellar has joined the company as Vice President of Research and Development. Kellar's knowledge in the field of tissue engineering, and experience in bringing products from concept through to commercial market, will be vital in enabling Histogen to meet the company's product launch goals in the coming year.

"I am excited to welcome Robert Kellar to our new, but rapidly growing, Histogen team," said Dr. Gail Naughton, CEO of Histogen. "With Rob on board, we look forward to reaching great milestones in 2008, including bringing our first tissue engineering products to market. Rob's appointment brings our senior management's total experience in tissue engineering to more than 50 years."

Dr. Kellar joins Histogen from his positions as co-owner and President of Development Engineering Sciences, a firm based in Flagstaff, Arizona. Kellar's prior experience in the biomedical industry includes positions with both W.L. Gore & Associates and Advanced Tissue Sciences, where he was involved with commercial worldwide management of research, product development, business, marketing, and sales. Kellar has authored over 7 papers and is the inventor on 5 patents and patent applications. Kellar also serves on the Scientific Advisory Board for Theregen, a cell therapy company investigating the cardiovascular applications of the cell-based human tissue patch, Anginera.

"Histogen's technology will afford the opportunity for a variety of product possibilities," said Dr. Robert Kellar. "I'm enthusiastic about joining the Histogen team and I look forward to the role we can play in advancing the field of tissue engineering and regenerative medicine."

Histogen, launched in 2007, seeks to redefine regenerative medicine by developing a series of high value products without the use of embryonic stem cells or animal products. Through Histogen's proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors from which the company has developed its rich product portfolio. Histogen's business plan benefits from the lessons learned at Advanced Tissue Sciences, and focuses on near, mid and long term products that are either self-pay or reimbursable.
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